Amazing RevUp31

Monday, May 21, 2012

Resveratrol molectular structure image

What is Resveratrol?

Resveratrol is a powerful antioxidant found in plants, certain nuts, and in heavy concentrations in the skins of red grapes. Resveratrol is produced naturally by plants when they under attack by environmental stresses such as bacteria or fungi. Resveratrol acts as a toxin to fight off unwanted attacking organisms in the plant’s cells. Resveratrol is a plants defense system. (21, 22)

What is so interesting about the fact that Resveratrol is found in high concentration in grapes, is the fact that French people typically have a fattier diet than Americans, yet they have less health issues that Americans. Particularly, the number of heart attacks amongst Europeans in general compared to Americans is staggeringly lower. (5)

This interesting finding is why people say red wine is good for your heart. As 60 Minutes reported in January 2009, scientists believe that the Resveratrol in red wine might do even more than just keep the heart healthy. In high concentrations they feel it could significantly extend life by preventing a number of age related illnesses.

wine bottle photo

In the 60 Minutes presentation one doctor said, "Our goal is to prevent and forestall many of the diseases that strike us as we reach 50, 60, and 70. All with one pill. I think we can slow down these genes that control the aging process."

Now speaking of high concentrations, lab studies found that a 150 lb person would have to consume 750 - 1,000 bottles of red wine every day to get enough Resveratrol necessary to achieve the results these studies are looking for. (14)

Activating the Human Anti-aging Gene... the EASY Way

Gene graphic

Did you know that you have an anti-aging gene in your body? Amazing isn’t it! Doctors refer to it as Gene 31. But unfortunately for us all, Gene 31 is not very active in our bodies. The fortunate news is, it CAN be activated!

Gene 31 is packed full of so many benefits that if consistently active in our bodies, it could considerably change our lives almost immediately. We can summarize the main, basic functions of Gene 31 in humans to repairing DNA and suppressing certain “bad” genes. It is these “bad” genes that can cause the proper functioning of cells to be destroyed, which can lead to the beginning of many diseases people suffer as they age. (2) Once activated, this amazing Gene 31 plays a critical role in fighting many of the diseases of aging, such as heart disease, Alzheimer’s, Parkinson’s, diabetes, even cancer! Some Doctors believe that as we get older, it actually becomes more difficult for Gene 31 to fight all of these “bad” genes that cause these diseases. As a result, perhaps this is why so many people end up with one or more of these conditions we associate with old age.

Aside from common diseases of aging, Gene 31 can also be effective in lowering cholesterol, blood pressure, and assisting in weightloss! (1) So we ALL obviously want this amazing Gene 31 to become more active in our bodies! Lets get to the details of how this can occur.

More On Resveratrol...

We’ve already mentioned that Resveratrol helps keep cells in our body safe from free radicals. We discussed its effects on the diseases related to aging. We mentioned its anti-aging benefits. Other recent studies claim that Resveratrol can improve the performance of the brain and heart, and increase the life-span of the cells in our bodies. Many nutritionists and health professionals prescribe Resveratrol for people with a poor immune system or who are recovering from an illness. Others prescribe it as an anti-inflammatory.

Researcher photo

What doctors are mainly focusing on is increasing the human lifespan by activating the body’s natural, genetic defenses against diseases using the Resveratrol which is found in our RevUp31 formula. Imagine being 90 yrs old and living like a 60 yr old! Imagine being 90 and playing tennis, running around with the grandkids, watching them graduate from college, traveling the world.

Do you like to go on diets, follow strict eating plans, eat foods you dislike, and eat a lot less than you’d prefer? Research has shown that DIETING is one very effective way of firing up Gene 31. Here is how it works - Consuming less calories causes a build up of a substance called nictotinamide adenine dinucleotide (NAD) in the cells of your body. NAD is usually busy converting glucose in the foods you are eating into energy. But if you are dieting and therefore eating less... NAD soon runs out of work and needs something else to do.

Turns out, NAD begins activating this powerful, yet relatively quiet anti-aging gene in our bodies - Gene 31!

Now obviously we’d like Gene 31 to be A LOT more active in our bodies. So the BIG QUESTIONS are...

Is there anything that acts like NAD in terms of activating our anti-aging Gene 31? If we don’t like the idea of dieting, is there a way to “trick” Gene 31 into thinking we are dieting? Can we mimick the anti-aging results of dieting, without actually dieting? Is there a pill that will just diet for us? Is there a natural substance that will activate Gene 31?

Amazingly, the answer is YES! It’s called Resveratrol.

Sources

  1. Elliott PJ, Jirousek, M. (2008). “Sirtuins: Novel targets for metabolic disease”. Current Opinion in Investigational Drugs
  2. Harvard Medical School Staff. Small Molecule Increases Lifespan and Healthspan of Obese Mice. Harvard Medical School Office of Public Affairs.
  3. Lu, C., Bambang, I.F., Armstrong, J.S., Whiteman, M. Resveratrol blocks high glucose-induced mitochondrial reactive oxygen species production in bovine aortic endothelial cells: role of phase 2 enzyme induction. Diabetes, Obesity & Metabolism, April 2008.
  4. Hingdon, Jane. Resveratrol. Linus Pauling Institute Micronutrient Research for Optimum Health, 2005. Updated 2008 by Drake, Victoria J.
  5. Mayo Clinic Staff. Red Wine and Resveratrol: Good for your Heart? Mayo Foundation for Medical Education and Research (MFMER), 2009.
  6. National Cancer Institute Staff. Red Wine and Cancer Prevention: Fact Sheet. National Cancer Institute (part of U.S. National Institutes of Health), 2002.
  7. http://en.wikipedia.org/wiki/Resveratrol#cite_note-pmid8985016-9: Jang M, Cai L, Udeani GO, Slowing KV, Thomas CF, Beecher CW, Fong HH, Farnsworth NR, Kinghorn AD, Mehta RG, Moon RC, Pezzuto JM (1997). “Cancer chemopreventive activity of Resveratrol, a natural product derived from grapes”.
  8. http://en.wikipedia.org/wiki/Resveratrol: Athar M, Back JH, Tang X, et al. (November 2007). “Resveratrol: a review of preclinical studies for human cancer prevention”
  9. Levi F, Pasche C, Lucchini F, Ghidoni R, Ferraroni M, La Vecchia C (April 2005). “Resveratrol and breast cancer risk”
  10. Garvin S, Ollinger K, Dabrosin C (January 2006). “Resveratrol induces apoptosis and inhibits angiogenesis in human breast cancer xenografts in vivo”.
  11. Borra, Margie T., Denu, John M., Smith, Brian C. Mechanism of Human SIRT1 Activation by Resveratrol. J. Biological Chemistry, Vol. 280, Issue 17, April 29, 2005.
  12. Lagouge M, Argmann C, Gerhart-Hines Z, et al. (2006). “Resveratrol improves mitochondrial function and protects against metabolic disease by activating SIRT1 and PGC-1alpha”.
  13. Barclay, Laurie M.D. Growing Evidence Links Resveratrol to Extended Life Span. Life Extension, March 2007.
  14. Valenzano DR, Terzibasi E, Genade T, Cattaneo A, Domenici L, Cellerino A (2006). “Resveratrol prolongs lifespan and retards the onset of age-related markers in a short-lived vertebrate”. Current Biology
  15. Karuppagounder SS, Pinto JT, Xu H, Chen HL, Beal MF, Gibson GE (November 2008). “Dietary supplementation with Resveratrol reduces plaque pathology in a transgenic model of Alzheimer’’’s disease”.
  16. Boocock DJ, Faust GE, Patel KR, et al. (June 2007). “Phase I dose escalation pharmacokinetic study in healthy volunteers of Resveratrol, a potential cancer chemopreventive agent”.
  17. Alcaín FJ, Villalba JM (April 2009). “Sirtuin activators”. Expert Opin Ther Pat
  18. Kaeberlein M, Kirkland KT, Fields S, Kennedy BK (September 2004). “Sir2-independent life span extension by calorie restriction in yeast”
  19. Kaeberlein M, McDonagh T, Heltweg B, et al. (April 2005). “Substrate-specific activation of sirtuins by Resveratrol”
  20. Bråkenhielm E, Cao R, Cao Y (August 2001). “Suppression of angiogenesis, tumor growth, and wound healing by Resveratrol, a natural compound in red wine and grapes”
  21. Cao Y, Fu ZD, Wang F, Liu HY, Han R (2005). “Anti-angiogenic activity of Resveratrol, a natural compound from medicinal plants”
  22. Hung LM, Chen JK, Huang SS, Lee RS, Su MJ (2000). “Cardioprotective effect of Resveratrol, a natural antioxidant derived from grapes”.

Additional Sources